Majority of first-wave COVID-19 clinical trials have significant design shortcomings, study finds Analysis of COVID-19 clinical trials as of late March finds quantity but less quality https://www.eurekalert.org/pub_releases/2020-06/jhub-mof060920.php ... In all, the 201 trials involved 92 distinct drugs as well as antibody-containing blood plasma.
Mehta and colleagues found that most of these trials demonstrated design weaknesses. For example, about a third had no defined clinical endpoint, such as hospital discharge or survival, by which success could be measured. About a quarter lacked the standard random assignment of patients to a candidate treatment or control/comparator drug. Of the 152 trials that did randomize patients to a treatment or comparator, only 55 involved the usual practice of 'blinding'--a bias-reducing strategy in which patients as well as doctors and others who direct care and assess outcomes are kept from knowing who received the treatment or placebo...
SAGE advises that measures relating to individual and household isolation will likely need to be enacted within the next two weeks to be fully effective, and those concerning social distancing of the elderly and vulnerable 2-3 weeks after this
Individual/Household isolation (of household with infected individual): by March 23 Social Distancing of elderly/vulnerable: 6th April - 13th April
Just as well the government didn't follow SAGE advice!
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
They've always been big on animal testing and the environment and things like that.
But JK Rowling has written movingly on her site of her own experiences of abuse and why (although she sympathises with trans people) why the experiences of women are different.
And she gets mocked by them.
It's got way more comments and replies than likes at the moment - and that's about as rare on Twitter as a Lib Dem poll lead.
Look at the cheek of this establishment backed, white scum; blocking the pavement & making a spectacle of himself whilst some poor young black lads tried to get their daily exercise
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
They've always been big on animal testing and the environment and things like that.
But JK Rowling has written movingly on her site of her own experiences of abuse and why (although she sympathises with trans people) why the experiences of women are different.
And she gets mocked by them.
It's got way more comments and replies than likes at the moment - and that's about as rare on Twitter as a Lib Dem poll lead.
2.5k replies to 2.1k likes barely even counts as a ratio.
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
They've just seen a big downward spike in merchandise.
There's a great Scott Galloway (NYU Stern School of Business) look at how Nike made the decision to back Kaepernick, it was entirely financially driven.
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
Surely not? I'm sure I read on here that it was the marketing disaster to end all marketing disasters? Of course it was then superseded by Gillette saying men should be a bit less rapey.
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
They've always been big on animal testing and the environment and things like that.
But JK Rowling has written movingly on her site of her own experiences of abuse and why (although she sympathises with trans people) why the experiences of women are different.
And she gets mocked by them.
It's got way more comments and replies than likes at the moment - and that's about as rare on Twitter as a Lib Dem poll lead.
2.5k replies to 2.1k likes barely even counts as a ratio.
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
Being woke is niche marketing. It can work if you build up your brand on that basis.
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
The GE of 2024 was decided the weekend of the Cummings revelations.
It only gets worse from there.
With respect that is just wrong
Cummings will not define this government, covid and leaving the EU will and the economic response
I do not think Boris will even see 2021out
Always appreciate your thoughts Big_G, but "covid and leaving the EU will and the economic response" will define the result. That's my point - it is downhill now.
The GE of 2024 was decided the weekend of the Cummings revelations.
It only gets worse from there.
While I would enjoy seeing the protracted and tortured weakening of this administration over the next three years and ten months and its final electoral humiliation in May 2024 as much as the next person, I'm much less convinced.
The honeymoon has clearly ended but that's a long way from saying defeat is on the cards. We know there is nothing the Conservatives are better at than clinging onto power - anything that money can buy (including votes) will be fair game.
A lot will depend on which school of thought prevails - there are those who think Covid-19 and the lockdown has wrecked the economy and the legacy of mass unemployment and the impoverishing of millions will cast a dark cloud over the country for a decade or more.
OTOH, there are those who see covid-19 more as a natural disaster from which recovery will be swift. They argue the middle classes in particular have done very well out of lockdown - working at home, relaxed and not spending (apart from online). They'll have plenty of cash to splash when the shops re-open and this will give the economy a huge boost ensuring most jobs are safe and life will swiftly return to normal.
As with all good schools, both have elements of truth - neither has a monopoly.
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
Being woke is niche marketing. It can work if you build up your brand on that basis.
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
It can also backfire when you're an established everyday brand with a broad customer base who then suddenly wades into politics.
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
Being woke is niche marketing. It can work if you build up your brand on that basis.
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
To quote Flight of the Conchords:
They're turning kids into slaves just to make cheaper sneakers But what's the real cost? Cause the sneakers don't seem that much cheaper Why are we still paying so much for sneakers When you got them made by little slave kids What are your overheads?
People making long term predictions are crazy. In December people were already writing off Labour's chances in 2024. In January Trump's position was actually looking stronger after the impeachment and Biden a busted flush. Who knows where we will be in September, never mind 2024.
This was a problem for Blair too. He overcame the problem by renaming the party New Labour. New Labour is no longer the reassurance it once was but a simple remarketing strategy would help.
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
They've just seen a big downward spike in merchandise.
There's a great Scott Galloway (NYU Stern School of Business) look at how Nike made the decision to back Kaepernick, it was entirely financially driven.
It can lead to a short-term spike in sales as the notoriety and debate drive brand awareness but do long-term damage.
There's a good article here. "Rob Frankel, a branding expert and author of “The Revenge of Brand X,” “but here’s where they went off the rails: when you start managing your brand for political rather than financial reasons, you swan dive into a meat grinder.”
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
Being woke is niche marketing. It can work if you build up your brand on that basis.
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
It can also backfire when you're an established everyday brand with a broad customer base who then suddenly wades into politics.
I think that Yougov poll is pretty clear.
It is clear, but often people say things in response to opinion polls and don't follow through.
So, for example, Tim Martin and his fecking Wetherspoon news pushing Brexit enrages me, but there are several things I like Wetherspoons for - and the same goes for the extreme Remainers from my knitting group.
Maybe your argument is that the risks are only one way, and only brands upsetting the right are at risk?
Indeed, Starmer is doing things in the wrong order. He's meant to dominate his party before he dominates the country. In his defence, he probably didn't anticipate the political and economic impact of covid-19 and the huge amount of help he has been given by the antics of the Conservative Government and its advisers.
There are clear signs the Corbyn-ites are being driven out of positions of power and while they may snipe and cause embarrassment at the margins (and in the marginals), I suspect the realisation of possible victory will bring them into some form of tacit support.
Overturning a Government majority of 80 isn't easy but it has been done - to be fair, if Starmer took 96 seats off Johnson after 14 years of Conservative rule (which is what Cameron did to Brown after 13 years of Labour rule) he wouldn't win a majority either but he would be in the business of forming a Government.
The GE of 2024 was decided the weekend of the Cummings revelations.
It only gets worse from there.
Your periodic reminder that Ed MIliband's Labour led David Cameron's Tories in the polling averages from late 2010, all of 2011, all of 2012, all of 2013, all of 2014, and was neck-and-neck right before election day in 2015.
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
I don't know about Nike but Paperchase went bust, and Gillette suffered from their "best men can be" ad too.
Did they? That's sad.
Personally that ad impressed me, but I'm not going to shave more than once a day to reflect that so had no impact on my expenditure.
Fair enough. Many people (myself included) found it hectoring and patronising.
I haven't bought Gillette since.
Which probably shows the diference between Gilette and Nike.
Gilette is a necessity, if you're buying razors, shaving foam etc you're doing so because you need to shave. Gilette need regular customers who regularly buy from them, but they can't buy more than they already are doing so, can only buy less. I'm not going to buy more than I already was, but you can buy less.
OTOH for Nike people make individual purchases that frankly aren't necessities. Someone who is impressed by Nike or want to show their support, or simply through the extra publicity can make a purchase they wouldn't have made otherwise and that's extra for Nike's bottom line.
Indeed, Starmer is doing things in the wrong order. He's meant to dominate his party before he dominates the country. In his defence, he probably didn't anticipate the political and economic impact of covid-19 and the huge amount of help he has been given by the antics of the Conservative Government and its advisers.
There are clear signs the Corbyn-ites are being driven out of positions of power and while they may snipe and cause embarrassment at the margins (and in the marginals), I suspect the realisation of possible victory will bring them into some form of tacit support.
Overturning a Government majority of 80 isn't easy but it has been done - to be fair, if Starmer took 96 seats off Johnson after 14 years of Conservative rule (which is what Cameron did to Brown after 13 years of Labour rule) he wouldn't win a majority either but he would be in the business of forming a Government.
That would require LD ministers in a Starmer Cabinet if he repeated Cameron's feat of 2010 which I suppose might finally see Momentum sod off in disgust by default
This was a problem for Blair too. He overcame the problem by renaming the party New Labour. New Labour is no longer the reassurance it once was but a simple remarketing strategy would help.
Blair already had big poll leads when he took over as leader and New Labour accelerated that.
Tory swing voters are still not ready to risk voting for a Starmer led Labour Party as they were ready to vote for Blair and New Labour
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
They've just seen a big downward spike in merchandise.
There's a great Scott Galloway (NYU Stern School of Business) look at how Nike made the decision to back Kaepernick, it was entirely financially driven.
It can lead to a short-term spike in sales as the notoriety and debate drive brand awareness but do long-term damage.
There's a good article here. "Rob Frankel, a branding expert and author of “The Revenge of Brand X,” “but here’s where they went off the rails: when you start managing your brand for political rather than financial reasons, you swan dive into a meat grinder.”
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
Being woke is niche marketing. It can work if you build up your brand on that basis.
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
Pretty much the only brands I can think of that I would think suits "woke" as part of the brands culture would be Body Shop and Lush. More the latter probably, Lush must be Queen of the "woke" brands.
Just wondering if you have been affected by Cunards decision not to saill before November. I had the idea you are sailing sometime to New York with them
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
Being woke is niche marketing. It can work if you build up your brand on that basis.
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
It can also backfire when you're an established everyday brand with a broad customer base who then suddenly wades into politics.
I think that Yougov poll is pretty clear.
It is clear, but often people say things in response to opinion polls and don't follow through.
So, for example, Tim Martin and his fecking Wetherspoon news pushing Brexit enrages me, but there are several things I like Wetherspoons for - and the same goes for the extreme Remainers from my knitting group.
Maybe your argument is that the risks are only one way, and only brands upsetting the right are at risk?
No, I think it does work both ways.
You're right that not everyone will follow through.
It depends on the product, the alternatives and how strongly how many people feel about it.
I'm just saying it's not a good idea, in business or in principle - I object to the politicisation of everything.
I was against early lockdown so I am not going to argue with Jenny Harries, but I do think relying on the model will be a public inquiry issue. Are we talking about the 13 year old code, non-peer reviewed, with bugs that I think she means?
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
I don't know about Nike but Paperchase went bust, and Gillette suffered from their "best men can be" ad too.
Did they? That's sad.
Personally that ad impressed me, but I'm not going to shave more than once a day to reflect that so had no impact on my expenditure.
Fair enough. Many people (myself included) found it hectoring and patronising.
I haven't bought Gillette since.
Which probably shows the diference between Gilette and Nike.
Gilette is a necessity, if you're buying razors, shaving foam etc you're doing so because you need to shave. Gilette need regular customers who regularly buy from them, but they can't buy more than they already are doing so, can only buy less. I'm not going to buy more than I already was, but you can buy less.
OTOH for Nike people make individual purchases that frankly aren't necessities. Someone who is impressed by Nike or want to show their support, or simply through the extra publicity can make a purchase they wouldn't have made otherwise and that's extra for Nike's bottom line.
I don't own a pair, but Next% Vaporfly Nikes are the quickest running trainer around right now and that's not just hype.
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
I don't know about Nike but Paperchase went bust, and Gillette suffered from their "best men can be" ad too.
Did they? That's sad.
Personally that ad impressed me, but I'm not going to shave more than once a day to reflect that so had no impact on my expenditure.
Fair enough. Many people (myself included) found it hectoring and patronising.
I haven't bought Gillette since.
Which probably shows the diference between Gilette and Nike.
Gilette is a necessity, if you're buying razors, shaving foam etc you're doing so because you need to shave. Gilette need regular customers who regularly buy from them, but they can't buy more than they already are doing so, can only buy less. I'm not going to buy more than I already was, but you can buy less.
OTOH for Nike people make individual purchases that frankly aren't necessities. Someone who is impressed by Nike or want to show their support, or simply through the extra publicity can make a purchase they wouldn't have made otherwise and that's extra for Nike's bottom line.
To be honest there are alternatives like Wilkinson Sword or Harry's.
This was a problem for Blair too. He overcame the problem by renaming the party New Labour. New Labour is no longer the reassurance it once was but a simple remarketing strategy would help.
Blair already had big poll leads when he took over as leader and New Labour accelerated that.
Tory swing voters are still not ready to risk voting for a Starmer led Labour Party as they were ready to vote for Blair and New Labour
2020 isn't 1997, it's still 1993!
1997 comes around again in 2024.
With the government under the cosh for Covid-19 and a massive economic aftershock on its way, bolstered by no deal, I don't see how this government navigates the next four years without losing rather than retaining support.
Johnson and/or his successors could pull rabbits from hats, although I can't see the rabbits or the hats at the moment..
Blimey, definitely unprovoked unlike the tea thing.
It's going down like a bucket of cold sick.
Even on Twatter.
Personally I've never shopped in that store, but I thought pretentious twats was kind of their brand identity?
Being woke is niche marketing. It can work if you build up your brand on that basis.
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
Pretty much the only brands I can think of that I would think suits "woke" as part of the brands culture would be Body Shop and Lush. More the latter probably, Lush must be Queen of the "woke" brands.
What about the Co-Op? Certainly their banking is pretty woke (even after unpleasantness of a few years ago). Their food stores walk the tightrope pretty well; right-ons will seek them out, but I'm not sure that anyone would be actively repelled by them.
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
They've just seen a big downward spike in merchandise.
There's a great Scott Galloway (NYU Stern School of Business) look at how Nike made the decision to back Kaepernick, it was entirely financially driven.
It can lead to a short-term spike in sales as the notoriety and debate drive brand awareness but do long-term damage.
There's a good article here. "Rob Frankel, a branding expert and author of “The Revenge of Brand X,” “but here’s where they went off the rails: when you start managing your brand for political rather than financial reasons, you swan dive into a meat grinder.”
Nike saw a big upward spike in sales when they backed Colin Kaepernick. Success breeds imitation.
I don't know about Nike but Paperchase went bust, and Gillette suffered from their "best men can be" ad too.
Did they? That's sad.
Personally that ad impressed me, but I'm not going to shave more than once a day to reflect that so had no impact on my expenditure.
Fair enough. Many people (myself included) found it hectoring and patronising.
I haven't bought Gillette since.
Which probably shows the diference between Gilette and Nike.
Gilette is a necessity, if you're buying razors, shaving foam etc you're doing so because you need to shave. Gilette need regular customers who regularly buy from them, but they can't buy more than they already are doing so, can only buy less. I'm not going to buy more than I already was, but you can buy less.
OTOH for Nike people make individual purchases that frankly aren't necessities. Someone who is impressed by Nike or want to show their support, or simply through the extra publicity can make a purchase they wouldn't have made otherwise and that's extra for Nike's bottom line.
To be honest there are alternatives like Wilkinson Sword or Harry's.
The GE of 2024 was decided the weekend of the Cummings revelations.
It only gets worse from there.
While I would enjoy seeing the protracted and tortured weakening of this administration over the next three years and ten months and its final electoral humiliation in May 2024 as much as the next person, I'm much less convinced.
The honeymoon has clearly ended but that's a long way from saying defeat is on the cards. We know there is nothing the Conservatives are better at than clinging onto power - anything that money can buy (including votes) will be fair game.
A lot will depend on which school of thought prevails - there are those who think Covid-19 and the lockdown has wrecked the economy and the legacy of mass unemployment and the impoverishing of millions will cast a dark cloud over the country for a decade or more.
OTOH, there are those who see covid-19 more as a natural disaster from which recovery will be swift. They argue the middle classes in particular have done very well out of lockdown - working at home, relaxed and not spending (apart from online). They'll have plenty of cash to splash when the shops re-open and this will give the economy a huge boost ensuring most jobs are safe and life will swiftly return to normal.
As with all good schools, both have elements of truth - neither has a monopoly.
I think this is a very good analysis. Coronavirus has a ways to play out yet, and there is still lots we don't know. But I think on balance there will be some heavy economic fallout which will start to impact on the middle classes, not to mention some strange bedfellows jostling in the queue at JobCentre Plus come the Autumn. But there is also plenty of time for Boris and Dom to ride this one out and tweak the narrative as things get back to normal towards the end of 2021.
Comments
That would be no bad thing after recent events, frankly.
https://twitter.com/bulamabukarti/status/1270391133961682944
Analysis of COVID-19 clinical trials as of late March finds quantity but less quality
https://www.eurekalert.org/pub_releases/2020-06/jhub-mof060920.php
... In all, the 201 trials involved 92 distinct drugs as well as antibody-containing blood plasma.
Mehta and colleagues found that most of these trials demonstrated design weaknesses. For example, about a third had no defined clinical endpoint, such as hospital discharge or survival, by which success could be measured. About a quarter lacked the standard random assignment of patients to a candidate treatment or control/comparator drug. Of the 152 trials that did randomize patients to a treatment or comparator, only 55 involved the usual practice of 'blinding'--a bias-reducing strategy in which patients as well as doctors and others who direct care and assess outcomes are kept from knowing who received the treatment or placebo...
And Read the full story takes me to the comments.
Even on Twatter.
https://twitter.com/LawDavF/status/1270784406060437510?s=20
https://www.itv.com/news/2020-06-10/uk-was-inundated-by-new-coronavirus-cases-from-abroad-genetic-analysis-reveals/
1. The Whitehouse have demanded an apology from CNN for publishing a poll showing Biden leading.
2. CNN's chief council is called D. C. VIGILANTE and that is totally boss.
https://twitter.com/CNNPR/status/1270802155201576962?s=19
https://twitter.com/GoodwinMJ/status/1270812775829450752?s=19
SAGE advises that measures relating to individual and household isolation will likely need to be enacted within the next two weeks to be fully effective, and those concerning social distancing of the elderly and vulnerable 2-3 weeks after this
Individual/Household isolation (of household with infected individual): by March 23
Social Distancing of elderly/vulnerable: 6th April - 13th April
Just as well the government didn't follow SAGE advice!
But JK Rowling has written movingly on her site of her own experiences of abuse and why (although she sympathises with trans people) why the experiences of women are different.
And she gets mocked by them.
It's got way more comments and replies than likes at the moment - and that's about as rare on Twitter as a Lib Dem poll lead.
https://twitter.com/crimeldn/status/1270801995230785544?s=21
Read it. And judge for yourself.
https://www.jkrowling.com/opinions/j-k-rowling-writes-about-her-reasons-for-speaking-out-on-sex-and-gender-issues/
Again I don't think Starmer has made much of an impact on public consciousness yet, it's not been the best time to take over as leader to be fair.
It only gets worse from there.
Cummings will not define this government, covid and leaving the EU will and the economic response
I do not think Boris will even see 2021out
https://twitter.com/Bernstein/status/1270427328590622720
He is still yet to complete the changes to reform and modernise and moderate his party Kinnock and John Smith managed let alone Tony Blair.
So even if he does become PM it is hard to see an overall majority for Labour at the next general election unless major changes are made
https://twitter.com/YouGov/status/1270682450574880768?s=20
If it turns out that you actually route your profits through a tax haven, or get children in South East Asia to manufacture your goods for a pittance, then it can backfire.
Personally that ad impressed me, but I'm not going to shave more than once a day to reflect that so had no impact on my expenditure.
I haven't bought Gillette since.
The honeymoon has clearly ended but that's a long way from saying defeat is on the cards. We know there is nothing the Conservatives are better at than clinging onto power - anything that money can buy (including votes) will be fair game.
A lot will depend on which school of thought prevails - there are those who think Covid-19 and the lockdown has wrecked the economy and the legacy of mass unemployment and the impoverishing of millions will cast a dark cloud over the country for a decade or more.
OTOH, there are those who see covid-19 more as a natural disaster from which recovery will be swift. They argue the middle classes in particular have done very well out of lockdown - working at home, relaxed and not spending (apart from online). They'll have plenty of cash to splash when the shops re-open and this will give the economy a huge boost ensuring most jobs are safe and life will swiftly return to normal.
As with all good schools, both have elements of truth - neither has a monopoly.
I think that Yougov poll is pretty clear.
They're turning kids into slaves just to make cheaper sneakers
But what's the real cost?
Cause the sneakers don't seem that much cheaper
Why are we still paying so much for sneakers
When you got them made by little slave kids
What are your overheads?
https://www.youtube.com/watch?v=GimzSBVQUDo
The main movement since GE19 is still LD to Labour not Tory to Labour
https://twitter.com/LettersOfNote/status/1270804176243736576?s=20
It does seem like an unnecessary own goal to piss of at least some of your consumers.
There's a good article here. "Rob Frankel, a branding expert and author of “The Revenge of Brand X,” “but here’s where they went off the rails: when you start managing your brand for political rather than financial reasons, you swan dive into a meat grinder.”
https://wjla.com/news/nation-world/nike-ad-puts-kaepernick-anthem-controversy-in-spotlight-days-before-launch-of-nfl-season
So, for example, Tim Martin and his fecking Wetherspoon news pushing Brexit enrages me, but there are several things I like Wetherspoons for - and the same goes for the extreme Remainers from my knitting group.
Maybe your argument is that the risks are only one way, and only brands upsetting the right are at risk?
There are clear signs the Corbyn-ites are being driven out of positions of power and while they may snipe and cause embarrassment at the margins (and in the marginals), I suspect the realisation of possible victory will bring them into some form of tacit support.
Overturning a Government majority of 80 isn't easy but it has been done - to be fair, if Starmer took 96 seats off Johnson after 14 years of Conservative rule (which is what Cameron did to Brown after 13 years of Labour rule) he wouldn't win a majority either but he would be in the business of forming a Government.
https://en.wikipedia.org/wiki/Opinion_polling_for_the_2015_United_Kingdom_general_election#/media/File:UK_opinion_polling_2010-2015.png
And that's why Ed Miliband won a majority in May 2015 and became Prime Minister... or not, as the case may be!
Perhaps inviting a male friend?
Gilette is a necessity, if you're buying razors, shaving foam etc you're doing so because you need to shave. Gilette need regular customers who regularly buy from them, but they can't buy more than they already are doing so, can only buy less. I'm not going to buy more than I already was, but you can buy less.
OTOH for Nike people make individual purchases that frankly aren't necessities. Someone who is impressed by Nike or want to show their support, or simply through the extra publicity can make a purchase they wouldn't have made otherwise and that's extra for Nike's bottom line.
I really see no upside for him. Furthermore crossover in the polls is becoming inevitable
He may cling on but either his health, covid or brexit will see him fail to go through 2021
https://medium.com/@rebeccarc/j-k-rowling-and-the-trans-activists-a-story-in-screenshots-78e01dca68d
https://twitter.com/BreakingNews/status/1270820951203164161?s=19
Tory swing voters are still not ready to risk voting for a Starmer led Labour Party as they were ready to vote for Blair and New Labour
1. At the start of lockdown Tory support went up as Lib Dem support went down.
2. As support for the government has fallen this has been reflected in an increase in support for Labour.
They declined significantly by August 2019 and P&G had to write it down.
It's true to say much of that is due to changing consumer habits on shaving. But this didn't help.
Just wondering if you have been affected by Cunards decision not to saill before November. I had the idea you are sailing sometime to New York with them
You're right that not everyone will follow through.
It depends on the product, the alternatives and how strongly how many people feel about it.
I'm just saying it's not a good idea, in business or in principle - I object to the politicisation of everything.
I use those now.
1997 comes around again in 2024.
With the government under the cosh for Covid-19 and a massive economic aftershock on its way, bolstered by no deal, I don't see how this government navigates the next four years without losing rather than retaining support.
Johnson and/or his successors could pull rabbits from hats, although I can't see the rabbits or the hats at the moment..
Some achievement, that!
(*I typed the word carefully)
I quite liked the Gillette advert, but then I am an out and proud Beta male. As my mother says "a lover, not a fighter"